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目的：观察犬冠状动脉左前降支（ＬＡＤ）阻断后，冠脉侧支血管建立的时间及表现，探讨侧支血管建立对左室功能的影响。材料和方法：杂种犬８条，开胸结扎ＬＡＤ，在结扎ＬＡＤ后１天～１年内定期行冠脉和左室造影。结果：结扎ＬＡＤ后１周，造影开始显示侧支血管建立；结扎ＬＡＤ后１～３个月，皆可见程度不等的侧支血管建立，左室功能明显改善。结论：犬冠脉有丰富的侧支血管；侧支血管的建立，有助于左室收缩功能的恢复。
OBJECTIVE: To observe the time and performance of establishing coronary collateral vessels after occlusion of left anterior descending coronary artery (LAD) in dogs and to explore the effects of collateral vessels on left ventricular function. MATERIALS AND METHODS: Eight crossbred dogs were thoracotomy lined with LAD, and coronary arteries and left ventriculography were performed regularly within 1 day to 1 year after ligation of LAD. Results: One week after ligation of LAD, angiography began to show the formation of collateral vessels. In 1-3 months after ligation of LAD, all of the collateral vessels with varying degrees were found and left ventricular function improved significantly. Conclusion: The canine coronary artery is rich in collateral vessels. The establishment of collateral vessels contributes to the recovery of left ventricular systolic function.