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目的:观察巴曲止血酶在鼻窦内窥镜手术时止血效果。方法:采用巴曲止血酶于术前30min肌肉注射1克氏单位(KU)与术中静脉滴注(静滴)2KU共观察51例,其中男性33例,女性18例,年龄为26±s21a。并与术前只行肌肉注射1KU的相同病人20例和不用任何止血药物的相同病人30例作对照。结果:巴曲止血酶肌注和静滴组的出血量为48±10mL,巴曲止血酶肌注组出血量为77±25mL,对照组出血量为111±40mL,3组间差异显著(P<0.01)。结论:巴曲止血酶用于鼻窦内窥镜手术的止血效果良好,未发生不良反应。
Objective: To observe the effect of batroxobin on hemostasis during endoscopic sinus surgery. Methods: Fifty-one patients were randomly divided into 1kg KU and 2KU Intravenous infusion (intravenous drip) 30min before operation, including 33 males and 18 females, with a mean age of 26 ± s21a . Twenty patients with the same patient who underwent intramuscular injection of 1 KU before surgery and 30 patients with the same patient without any hemostatic drug were compared. RESULTS: Bleeding volume of intraperitoneal and intravenous infusion of batroxobin was 48 ± 10 mL, bleeding volume of intraperitoneal injection of batroxobin was 77 ± 25 mL, and blood loss of control group was 111 ± 40 mL (P <0.01). CONCLUSION: Bartox blockade is effective for hemostasis in endoscopic sinus surgery. No adverse reactions occurred.