大井口边草(Pteris cretica)为凤尾蕨科,生长于日本温带地区。作者曾报道从其根茎中分离出一些蕨素型倍半萜和内-贝壳杉烷型二萜成分。最近从两种产地的蕨叶中分离出四个新型内-贝壳杉烷型甙类化合物。 从千叶县Yoko-o采集的大井口边草的风干后的叶中分离出二个新的内-贝壳杉烷 Pteris cretica is Pteridaceae, which grows in temperate regions of Japan. The authors have reported the isolation of ferrigenous sesquiterpene and endo-kaurane diterpenoids from their rhizomes. Recently, four novel endo-kaurane type terpenoids have been isolated from fern leaves in two production areas. Two new endo-kaukanes were isolated from the dried leaves of O. scrophularia collected from Yoko-o, Chiba Prefecture.