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目的观察中药血必净对多脏器功能障碍综合征(MODS)患者血清炎症介质的影响。方法51例MODS患者随机分为血必净治疗组和对照组,检测两组患者治疗前与治疗后TNF-α、CRP、IL-6水平变化。结果两组患者治疗后,血清炎症介质TNF-α、CRP、IL-6水平均较治疗前下降,但血必净治疗组下降更为显著。结论中药血必净有较好的控制炎症介质的作用,可能对改善MODS患者的预后产生积极的影响。
Objective To observe the effect of Xuebijing on serum inflammatory mediators in patients with multiple organ dysfunction syndrome (MODS). Methods 51 patients with MODS were randomly divided into Xuebijing treatment group and control group. The levels of TNF-α, CRP and IL-6 before and after treatment were detected in both groups. Results After treatment, serum inflammatory cytokines TNF-α, CRP, and IL-6 levels in the two groups were lower than those before treatment, but they were more significantly decreased in the Xuebijing group. Conclusion The Chinese medicine Xuebijing has a good effect on the control of inflammatory mediators and may have a positive effect on improving the prognosis of patients with MODS.