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EndraIazine,又称BQ22—708,是6苯酰—3肼基—5.6.7.8四羟基吡啶并—(4.3—c)—哒嗪甲磺酰盐,其化学结构与肼笨哒嗪有关; 对高血压的研究表明,此药系一作用强大的小动脉扩张剂,其有效剂量范围窄,毒性作用较小。这项研究系确定慢性充血性心力衰竭患者口服此药后的急性血流动力学效应。
EndraIazine, also known as BQ22-708, is 6-benzoyl-3-hydrazinyl-5.6.7.8 tetrahydroxypyrido- (4.3-c) -pyridazine mesylate, Blood pressure studies have shown that this medicine is a powerful small arterial vasodilator, its effective dose range narrow, less toxic effects. The study was designed to determine the acute hemodynamic effects of this medicine in patients with chronic congestive heart failure.