论文部分内容阅读
目的：观察桂哌齐特治疗缺血性脑梗死的疗效。方法：８５例脑梗死病人随机分为治疗组５５例（男性４４例，女性１１例，年龄６４±ｓ５ｄ），采用桂哌齐特３２０ｍｇ加入１０％葡萄糖或０．９％氯化钠２５０ｍＬ，静脉滴注（静滴），ｑｄ，连用１３ｄ，随后桂哌齐特２片（２００ｍｇ／片），ｐｏ，ｔｉｄ，连服５０ｄ。对照组３０例（男性２３例，女性７例，年龄６２±５ａ），采用右旋糖酐－４０，５００ｍＬ加复方丹参注射液１０ｍＬ，静滴，ｑｄ，连用１５ｄ。结果：治疗组总有效率９８％，优于对照组７０％（Ｐ＜０．０５）；起效快于对照组（治疗组４ｄ内起效占４０例，对照组仅４例）；治疗组且有使凝血因子Ｉ、血细胞比容、胆固醇显著下降及缺血性ＳＴ－Ｔ波显著改善作用。结论：桂哌齐特值得推荐治疗缺血性脑梗死。
Objective: To observe the effect of Cinepazide on ischemic cerebral infarction. Methods: Eighty-five patients with cerebral infarction were randomly divided into treatment group (44 males and 11 females, age 64 ± s5d). The patients were treated with cinepazide 320mg, 10% glucose or 0.9% sodium chloride 250mL, Instillation (intravenous drip), qd, once every 13d, followed by cinepazide 2 tablets (200mg / tablet), po, tid, and even served 50d. Control group of 30 patients (23 males and 7 females, age 62 ± 5a), using dextran 40,500 mL plus compound Danshen injection 10mL, intravenous infusion, qd, once every 15d. Results: The total effective rate of the treatment group was 98%, which was better than that of the control group (P <0.05); the onset rate was faster than that of the control group (40 cases in the treatment group within 4 days and 4 cases in the control group) And make coagulation factor I, hematocrit, significantly decreased cholesterol and ischemic ST-T wave significantly improved. Conclusion: Cinepazide is recommended for the treatment of ischemic cerebral infarction.