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根据不同的乙肝病毒标志,将患者分成四组:HBeAg(+)组,抗HBe(+)组;HBVDNA(+)组(包括DNAP同时阳性);及“四阴组” (e系统、HBVDNA、DNAP及抗HBc-IgM均阴性,其它乙肝病毒标志可阳性)。比较他们的血清IL-2值,结果如下:1.四组患者的IL-2水平都极显著低于健康对照组(p<0.01)。2.与“四阴组”比较,HBeAg(+)组偏低明显(p<0.01),HBVDNA(+)组偏低比较明显(p<0.05),抗HBe(+)组不显示差异(p>0.05)。3.HBeAg(+)组、抗HBe(+)组及HBVDNA(+)组之间IL-2无明显差异(p>0.05)。
The patients were divided into four groups according to the different hepatitis B virus markers: HBeAg (+) group, anti-HBe (+) group; HBVDNA group (including DNAP positive at the same time) DNAP and anti-HBc-IgM were negative, other hepatitis B virus markers can be positive). Their serum IL-2 levels were compared and the results were as follows: 1. IL-2 levels in all four groups were significantly lower than those in healthy controls (p <0.01). The level of HBeAg (+) was significantly lower (p <0.05), and the level of anti-HBe (+) was not significantly different > 0.05). There was no significant difference in IL-2 between HBeAg (+) group, anti-HBe (+) group and HBVDNA (+) group (p> 0.05).