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微生物产生的次级代谢产物具有各种不同的生物活性,抗生素是人们熟悉的具有抗微生物、抗病毒、抗肿瘤等作用的微生物次级代谢产物。自从40年代初青霉素被用于临床以来,抗生素为人类作出了卓越的贡献。1942年链霉素的发现者waksman首先下的定义是:“抗生素是微生物在其代谢过程中所产生的具有抑制它种微生物生长及活动甚至杀灭它种微生物性能的化学物质。”随着这一研究和应用领域的迅速发展,抗生素一词的含
Secondary metabolites produced by microorganisms have a variety of different biological activities. Antibiotics are familiar secondary metabolites of microorganisms with anti-microbial, anti-virus and anti-tumor effects. Antibiotics have made outstanding contributions to humankind since penicillin was used clinically in the early 1940s. In 1942, the creator of streptomycin, waksman, first defined it as: “An antibiotic is a chemical produced by a microorganism in its metabolism that inhibits the growth and activity of its micro-organism and even kills its micro-organism.” With the rapid development in this area of research and applications, the term antibiotic is included