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目的阶段性分析评价清镇市现行化疗方案对涂阳肺结核患者的疗效,适时调整和改进控制措施。方法回顾性分析市CDC结防门诊《结核病患者登记本》中2008—2012年涂阳肺结核患者治疗2月末痰菌转阴及疗效情况。结果2008—2012年涂阳肺结核治疗丢失率为4.5%(51/1145),其中复治涂阳患者丢失率高于初治涂阳患者。1 094例按初、复治方案治疗后,2月末痰菌转阴率90.8%,而2月末痰菌未转阴组治疗前痰菌阳性等级分组平均秩次高于转阴组。治疗前患者痰菌结果对2月末痰菌转阴有重要影响。“治愈组”与“失败组”痰菌阳性等级平均秩次类似。总治愈率为92.4%(1 011/1 094),初治涂阳治愈率(93.3%)高于复治涂阳(88.0%)。结论现行化疗方案在我市治疗初、复治涂阳肺结核患者均能达到满意效果。
Objective To analyze and evaluate the curative effect of the current chemotherapy regimen in Qingzhen on patients with smear positive pulmonary tuberculosis and to adjust and improve the control measures timely. Methods A retrospective analysis of the city of CDC clinics, “TB patient registration book” 2008-2012 smear-positive pulmonary tuberculosis patients at the end of 2 treatment of sputum negative conversion and efficacy. Results The loss rate of smear-positive pulmonary tuberculosis in 2008-2012 was 4.5% (51/1145), of which the rate of loss of smear-positive patients was higher than that of smear-positive patients. 1 094 cases according to the initial and retreatment programs after the end of February sputum negative conversion rate of 90.8%, while the end of February sputum bacteria untreated sputum positive sputum positive grade group before the treatment group was higher than the negative rank. Before treatment, sputum bacteria in patients with sputum bacteria at the end of February have a significant impact on the negative. “Cure group ” and “failure group ” sputum positive rank average rank similar. The total cure rate was 92.4% (1 011/1 094). The cure rate of newly diagnosed smear-positive smears was 93.3% higher than that of smecta-smear-positive smears (88.0%). Conclusion The current chemotherapy regimen in the city early treatment, retreatment smear positive pulmonary tuberculosis patients can achieve satisfactory results.