慢性肛瘘以往均采用手术治疗 ,但常需麻醉并可能致括约肌功能损害。近来研究发现化学性括约肌切开术治疗慢性肛瘘是一种有效的方法 ,即用药物降低肛管静息压 ,产生括约肌切开术的效果 ,而避免了括约肌功能的损害 ,甘油三硝酸盐是最常用的试剂。局部应用 0 .0 2 %的甘油三硝酸盐 Chronic anal fistula surgery in the past are used, but often require anesthesia and may cause sphincter dysfunction. Recent studies have found that chemical sphincterotomy for the treatment of chronic anal fistula is an effective way to reduce the resting pressure of the anal canal drugs, resulting in sphincterotomy effect, and to avoid the damage of sphincter function, glycerol trinitrate is The most commonly used reagent. Topically apply 0.022% of glycerol trinitrate