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目的观察三维适形放疗同步化疗治疗食管癌疗效、不良反应。方法 24例食管癌患者随机分两组,研究组12例:放疗+化疗,化疗采用DF方案,放疗剂量70Gy;对照组12例:单纯外照射。结果研究组与对照组完全缓解率为33.3%和8.3%,有效率为100%和66.7%。研究组不良反应与对照组两组差异无统计学意义。结论研究组治疗食管癌近期疗效和局部控制率较好,不良反应与对照组比较差异无统计学意义。
Objective To observe the efficacy and adverse reactions of three-dimensional conformal radiotherapy with concurrent chemotherapy in the treatment of esophageal cancer. Methods Twenty-four patients with esophageal cancer were randomly divided into two groups. The study group consisted of 12 cases with radiotherapy and chemotherapy. The DF regimen was used for chemotherapy and the dose of radiotherapy was 70 Gy. In the control group, 12 cases were treated with external irradiation alone. Results The complete remission rate was 33.3% in the study group and 8.3% in the control group. The effective rates were 100% and 66.7% respectively. There was no significant difference between the two groups in adverse reactions of the study group and the control group. Conclusions The study group has good short-term curative effect and local control rate in esophageal cancer treatment. There is no significant difference between the adverse reactions and the control group.