论文部分内容阅读
目的探讨泌尿系反复感染致病菌的发病特点及细菌L型感染的致病性,为临床诊治提供科学依据。方法将127例清洁中段尿培养确诊的反复发作肾盂肾炎患者,根据致病菌分为细菌型组、细菌伴L型组和细菌L型组,健康体检者为对照组,分析4组患者尿N-乙酰-β-D-氨基葡萄糖苷酶(NAG)、尿视黄醇结合蛋白(RBP)水平变化。结果泌尿系感染各组尿NAG和尿RBP较正常对照组均有不同程度升高,差异有非常显著性(P<0.01),单纯细菌L型感染患者较细菌型及细菌伴L型患者稍低,但细菌型、细菌伴L型及细菌L型3组之间差异无显著性(P>0.05)。结论细菌L型在泌尿道感染反复发作中占重要地位,泌尿系细菌L型感染具有致病性。
Objective To investigate the pathogenesis of recurrent urinary tract pathogens and the pathogenicity of bacterial L-type infection, and provide a scientific basis for clinical diagnosis and treatment. Methods A total of 127 patients with recurrent pyelonephritis confirmed by urinary culture in the middle of cleaning were enrolled. According to the pathogenic bacteria, they were divided into bacteria group, bacteria with L type group and bacterial L type group, and healthy people as the control group. The urinary N - acetyl-β-D-glucosaminidase (NAG), urinary retinol binding protein (RBP) levels. Results Urinary NAG and urinary RBP levels in urinary tract infection groups were significantly higher than those in normal control group (P <0.01). Patients with L-type bacterial infection were slightly lower than those with bacterial and bacterial L-forms , But there was no significant difference between bacterial type, bacterial type L and bacterial L type 3 (P> 0.05). Conclusion Bacterial L-type occupies an important position in recurrent urinary tract infections, and L-type bacterial infection in urinary tract is pathogenic.