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目的分析温州市艾滋病抗病毒治疗死亡病例流行病学特征,为降低病人病死率,提高艾滋病抗病毒治疗效果提供参考依据。方法从国家“艾滋病综合防治信息系统—抗病毒治疗管理”数据库收集相关信息,建立Excel数据库并用SPSS17.0软件进行分析。结果全市累计治疗死亡病例94例,男性占86.2%,女性占13.8%,死亡病例平均年龄(55.55±15.27)岁,治疗病死率为7.2%,开始治疗时CD4+T淋巴细胞≤50个/μl病人病死率为18.0%,CD4+T淋巴细胞51~200个/μl病人病死率为7.5%,CD4+T淋巴细胞>200个/μl病人病死率为2.6%;大部分病例死于艾滋病相关疾病,占总病例的59.6%;在治疗3个月内死亡占54.2%,12个月内死亡的占70.2%。结论温州市艾滋病抗病毒治疗死亡病例治疗时机较晚,应加强病人的早期发现和及时治疗,才能有效地降低病人病死率,提高治疗效果。
Objective To analyze the epidemiological characteristics of death caused by AIDS virus in Wenzhou City and provide reference for reducing the mortality of patients and increasing the effect of AIDS virus antiviral therapy. Methods The relevant information was collected from the national “AIDS Integrated Prevention and Control Information System - Antiviral Treatment Management” database, and an Excel database was established and analyzed by SPSS17.0 software. Results The total number of deaths in the city was 94, accounting for 86.2% for males and 13.8% for females. The average age of deaths was 55.55 ± 15.27 years. The treatment mortality rate was 7.2%. CD4 + T lymphocytes ≤50 / μl The case fatality rate was 18.0%. The case fatality rate was 7.5% for CD4 + T lymphocytes from 51 to 200 cells / μl and 2.6% for CD4 + T lymphocytes> 200 cells / μl. The majority of cases died of AIDS-related diseases Accounting for 59.6% of the total cases; 54.2% died within 3 months of treatment and 70.2% died within 12 months. Conclusions The death of HIV-AIDS patients in Wenzhou City is relatively late, and the early detection and timely treatment of patients should be strengthened to effectively reduce the patient’s mortality and improve the treatment effect.