皮肤是免疫学活性部位 ,而且是受人关注的接种途径。作者先前研究发现 ,用极小剂量的粉状流感疫苗表皮粉剂免疫 ( EPI)小鼠可诱导保护性免疫应答。在此项研究中 ,作者将常用铝佐剂和含 Cp G基元 ( Cp G DNA)的合成寡核苷酸运用于 EPI,观察这些佐剂增强免疫应答的效果。作者以白 The skin is an immunologically active site and is a route of concern to people. Previous studies by the authors found that epidermal powder immunized (EPI) mice with a minimal dose of the powdery influenza vaccine induced a protective immune response. In this study, the authors used synthetic aluminum adjuvants and synthetic oligonucleotides containing CpG motifs (CpG DNA) in EPI and observed the effect of these adjuvants in enhancing the immune response. The author is white