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为了确定缺血性脑血管病患者rCBF与重分配(RD)间的关系及其临床意义,作者以异丙基-~(123)I-碘 苯丙胺(~(123)-I-IMP)为示踪剂,用SPECT对16例单侧完全性卒中患者(男14,女2,年龄26～77岁,平均58岁)及年龄相当右利健康者10人进行了研究。患者于卒中后1～7(平均2.6)月间行~(123)I-IMP SPECT检查。5例作了颞浅动脉与大脑中动脉(STA-MCA)搭桥术,6个多月后复查~(123)I-IMP SPECT。rCBF及RD在注射~(123)I-IMP后10～30min和3～5h,从SPECT的早期和延迟的影像所显示的梗塞区与其周边示踪剂的活度差别确定。rCBF按F=R×Cb/
In order to determine the relationship between rCBF and redistribution (RD) in patients with ischemic cerebrovascular disease and its clinical significance, the authors use isopropyl-123-iodoamphetamine (~ (123) -I-IMP) SPECT was performed on 16 patients with unilateral complete stroke (male 14, female 2, aged 26-77, mean 58 years) and 10 right-eared right-healthy individuals. Patients underwent ~ (123) I-IMP SPECT at 1-7 months (mean 2.6 months) after stroke. Five patients underwent superficial temporal artery and middle cerebral artery (STA-MCA) bypass surgery. After more than 6 months, ~ (123) I-IMP SPECT was retrospectively reviewed. rCBF and RD were determined from the differences in activity between the infarcted area and the surrounding tracer as revealed by early and delayed SPECT imaging at 10-30 min and 3-5 h after ~ (123) I-IMP injection. rCBF Press F = R × Cb /