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目的分析冠心病患者白蛋白尿和血清尿酸水平之间存在的关系。方法 86例冠心病患者,将其中43例在24 h内尿液中白蛋白为阳性的患者作为A组,43例阴性患者作为B组。患者住院的第2天对血清尿酸(UA)、尿素氮(BUN)、血清肌酐(Scr)、空腹血糖(FPG)指标实施监测。结果检测后,A组患者的UA、BUN、Scr和FPG等方面的指标水平明显高于B组,差异有统计学意义(P<0.05)。血清尿酸是造成冠心病患者出现白蛋白尿的独立危险因素,相对危险比是0.97,95%的可信区间是0.97,1.02(P<0.05)。结论患者患有冠心病后,白蛋白尿与血清尿酸存在关联,血清尿酸可被视为诱发冠心病患者发生白蛋白尿的隐患的独立因素,在实际治疗过程中需要重点关注。
Objective To analyze the relationship between albuminuria and serum uric acid in patients with coronary heart disease. Methods A total of 86 patients with coronary heart disease were enrolled in this study. A group of 43 patients with positive albumin in urine within 24 hours and 43 negative patients as group B. Patients were monitored on the second day of hospitalization for serum UA, BUN, Scr and FPG. Results After the test, the levels of UA, BUN, Scr and FPG in group A were significantly higher than those in group B, the difference was statistically significant (P <0.05). Serum uric acid was an independent risk factor for albuminuria in CHD patients with a relative risk ratio of 0.97 and a 95% confidence interval of 0.97 and 1.02, respectively (P <0.05). Conclusions Patients with coronary heart disease, albuminuria and serum uric acid is related to serum uric acid can be considered as an independent risk factor for the development of albuminuria in patients with coronary heart disease in the actual treatment needs to be focused.