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目的观察奥曲肽联合垂体后叶素治疗脑梗死患者服用阿司匹林致消化道出血的临床疗效。方法选取因服用阿司匹林抗凝引起消化道出血的脑梗死患者66例,随机分为观察组与对照组各33例。2组均予常规方法治疗消化道出血,对照组加用垂体后叶素治疗,观察组在对照组基础上联合奥曲肽治疗。比较2组临床效果、平均止血时间与平均住院时间。结果观察组总有效率为84.9%,高于对照组的66.7%(P<0.01);观察组平均止血时间、平均住院时间均较对照组短(P<0.01)。结论奥曲肽联合垂体后叶素治疗脑梗死患者服用阿司匹林致消化道出血疗效果满意,值得临床推广应用。
Objective To observe the clinical efficacy of octreotide combined with pituitrin in the treatment of patients with cerebral infarction taking aspirin-induced gastrointestinal bleeding. Methods Sixty-six patients with cerebral infarction caused by taking aspirin anticoagulant were randomly divided into observation group and control group with 33 cases each. Both groups were given routine treatment of gastrointestinal bleeding, the control group plus pituitrin treatment, the observation group on the basis of the control group combined with octreotide treatment. The clinical effects, mean hemostasis time and average length of stay in two groups were compared. Results The total effective rate in observation group was 84.9%, which was higher than that in control group (66.7%, P <0.01). The average hemostasis time and average length of stay in observation group were shorter than those in control group (P <0.01). Conclusion octreotide combined with pituitrin in patients with cerebral infarction aspirin-induced gastrointestinal bleeding satisfactory results, it is worth promoting the clinical application.