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目的分析奥沙利铂联合卡培他滨治疗晚期胃癌的临床疗效。方法将本院消化内科2008年8月至2012年8月诊治的56例晚期胃癌患者分成观察组和对照组(各28例),观察组给予奥沙利铂联合卡培他滨化疗,对照组给予顺铂联合5-氟尿嘧啶、亚叶酸钙化疗,均完成两个周期后进行疗效对比分析。结果观察组总有效15例(53.6%),对照组总有效10例(35.7%)。所有患者在治疗中均未出现严重不良反应。结论奥沙利铂联合卡培他滨治疗晚期胃癌有较好疗效,值得临床广泛应用。
Objective To analyze the clinical efficacy of oxaliplatin plus capecitabine in the treatment of advanced gastric cancer. Methods 56 patients with advanced gastric cancer diagnosed and treated in our hospital from August 2008 to August 2012 were divided into observation group and control group (28 cases each). The observation group was given oxaliplatin combined with capecitabine chemotherapy and the control group Given cisplatin combined with 5 - fluorouracil, leucovorin chemotherapy, were completed after two cycles of comparative efficacy analysis. Results The total effective rate was 15.6% in the observation group and 10.7% in the control group (35.7%). All patients in the treatment of no serious adverse reactions. Conclusion Oxaliplatin combined with capecitabine in the treatment of advanced gastric cancer has a good curative effect, which is worthy of clinical application.