1临床资料患者男,69岁。全身多处角化性丘疹、斑块2年,溃疡半年。40余年前,因哮喘间断口服中药(具体不详),一年半后全身逐渐出现淡褐色及白色斑疹,随年龄增长渐增多,变大。十余年前双手、足部开始出现角化性丘疹、斑块且渐增多,密集。2年前全身多处出现角化性丘疹,斑块。近半年来角化性丘疹,斑块皮损局部出现破溃,形成溃疡。既往有哮喘、黄疸性肝炎 1 Clinical data Patient male, 69 years old. Multi-body keratosis papules, plaque 2 years, 6 months ulcer. More than 40 years ago, due to intermittent oral administration of traditional Chinese medicine (specifically unknown), a year and a half after the gradual emergence of light brown and white rash, with increasing age, increasing, larger. More than ten years ago hands, feet began to appear keratosis papules, plaques and more and more intensive. 2 years ago the body appears multiple keratosis papules, plaques. In the past six months, keratosis papules, plaque lesions appear to ulceration ulceration. Past with asthma, jaundice hepatitis