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狼疮性肾炎 (ＬＮ )是由体液免疫和细胞免疫共同参与的自身免疫性疾病。ＩＬ 13可抑制细胞免疫 ,促进Ｂ细胞的增殖和抗体的分泌。我们检测了ＬＮ患者血浆及肾组织ＩＬ 13的表达 ,并分析其与肾功能及狼疮活动指标的相关关系 ,探讨ＩＬ 13在ＬＮ发病机制及其活动性病变中的作用。
Lupus nephritis (LN) is an autoimmune disease that is jointly involved in humoral and cellular immunity. IL 13 inhibits cellular immunity, promotes B cell proliferation and antibody secretion. We examined the expression of IL-13 in the plasma and kidney tissue of patients with LN, and analyzed its correlation with renal function and lupus activity index to explore the role of IL-13 in LN pathogenesis and its active lesions.