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目的观察氨茶碱、纳洛酮联合治疗极低出生体重儿(VLBWI)呼吸暂停的临床效果。方法对2000年1月～2008年7月的156例极低出生体重儿随机分为两组,治疗组88例在应用氨茶城的基础上加用纳洛酮,对照组68例单用氨茶城。结果治疗组显效率69.32%,总有效率88.64%,对照组显效率48.53%,总有效率70.59%;P<0.01,差异均具有统计学意义。结论氨茶城和纳洛酮联合治疗极低出生体重儿呼吸哲停比单用氮茶碱效果好,值得临床推广。
Objective To observe the clinical effect of aminophylline and naloxone in the treatment of apnea of very low birth weight infants (VLBWI). Methods From January 2000 to July 2008 156 cases of very low birth weight children were randomly divided into two groups, the treatment group of 88 patients on the basis of the application of ammonia tea city with naloxone, the control group of 68 patients with ammonia alone Tea City. Results The effective rate of the treatment group was 69.32%, the total effective rate was 88.64%, the effective rate of the control group was 48.53%, the total effective rate was 70.59%; P <0.01, the differences were statistically significant. Conclusion Ammonia tea and naloxone combined treatment of very low birth weight children with respiratory and phlebitis than with theophylline alone is good, worthy of clinical promotion.