小细胞性肺癌即国际卫生组织(WHO)分类中的小细胞未分化癌,燕麦细胞癌是小细胞性肺癌中的一个亚型。1926年 Barnard 首先提出的称为“纵隔燕麦细胞肉瘤”的病例,事实上是1例原发性的燕麦细胞肺癌。直至1959年后,Azzopardi 等将其列为一种特殊类型的肺癌。因其细胞起源、病理改变、临床表现、治疗的反应和预后等均有别于其他类型的肺癌,故渐渐引起人们的重视。细胞起源和病理特点Bensch(1965)首先证明,燕麦细胞癌和类癌一样均起源于支气管粘膜的 Kul Small cell lung cancer is a small cell undifferentiated carcinoma of the World Health Organization (WHO) classification. Oat cell carcinoma is a subtype of small cell lung cancer. Barnard first proposed in 1926 called “mediastinal oat cell sarcoma” case, in fact, is a case of primary oat cell lung cancer. It was not until 1959 that Azzopardi classified it as a special type of lung cancer. Because of its origin of cells, pathological changes, clinical manifestations, treatment response and prognosis are different from other types of lung cancer, it gradually attracted people’s attention. Cell Origin and Pathology Bensch (1965) first demonstrated that oat cell carcinomas, like carcinoids, originate from the bronchial mucosa of Kul