论文部分内容阅读
在电镜下观察了加味温胆汤对Ｄ－半乳糖亚急性衰老大鼠大脑皮质神经元超微结构改变的影响，并对其主要细胞器进行了计量分析。结果表明：模型组脂褐素数量较正常组增多（Ｐ＜０．０５），线粒体则减少（Ｐ＜０．０５）同时还发现溶酶体、脂褐素大小形态不规则，线粒体肿胀、变性、嵴断裂、空泡样变，核膜内褶断裂，核仁边移等衰老改变，而加味温胆汤则使上述变性程度减轻，从而表明该方能延缓脑衰老，并提示该方可能具有稳定神经细胞生物膜系统作用。
The effects of Jiawei Wendan Decoction on ultrastructural changes of cerebral cortical neurons in rats with subacute aging of D-galactose were observed under electron microscope, and the main organelles were analyzed quantitatively. The results showed that the number of lipofuscin in the model group was higher than that in the normal group (P<0.05) and the mitochondria were decreased (P<0.05). Meanwhile, the size and shape of the lysosome and lipofuscin were irregular, and the mitochondria were swollen and degenerated. The aging of the nucleus and the nucleus of the nucleus, the nucleus in the nucleus, and the shift of the nucleolus, etc., and the Modified Wendan Decoction reduce the degree of degeneration, suggesting that this side can delay brain aging, and suggest that the party may have Stabilize the function of the nerve cell biofilm system.