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目的探讨CT引导下放射性~(125)Ⅰ组织间种植治疗头颈部恶性肿瘤的可行性。方法搜集整理我院2006年6月~2008年12月,对26例头颈部癌术后或放化疗后复发或转移患者行植放射性~(125)Ⅰ组织间种植治疗患者的临床资料。结果 26例均顺利完成手术,每例种植粒子12~54颗,中位数23颗。术后未发生出血、感染、粒子移位等严重并发症。28例随访3~24个月,平均16个月,局部控制率术后3个月为54%(14/26),6个月72%(18/25),12个月47%(11/23),2年37%(6/16)。结论放射性~(125)Ⅰ粒子种植治疗头颈部肿瘤是一种安全、有效、可行的治疗方法,其近期疗效值得肯定。
Objective To investigate the feasibility of CT-guided radiotherapy in the treatment of head and neck malignant tumors. Methods The clinical data of 26 patients with recurrent or metastatic head and neck cancer after radiotherapy or (125) Ⅰ interbody transplantation were collected from June 2006 to December 2008 in our hospital. Results All the 26 cases completed the operation smoothly, with 12 ~ 54 seeds per plant, with a median of 23. No postoperative bleeding, infection, particle displacement and other serious complications. 28 cases were followed up for 3-24 months with an average of 16 months. The local control rate was 54% (14/26) at 3 months, 72% (6/26) at 6 months, 47% at 12 months (11 / 23), 2 years 37% (6/16). Conclusion Radioactive 125I seed implantation in the treatment of head and neck cancer is a safe, effective and feasible treatment, and its immediate effect is worthy of confirmation.