为进一步观察恩丹西酮对化疗期间顺铂引起恶心呕吐的控制效果及使用剂量 ,采用自身对照方法观察 3 4例不同治疗周期用康泉与恩丹西酮控制顺铂所致的恶心呕吐。结果 ,恶心控制率 :康泉为 85 2 % ,恩丹西酮为 82 3 % ;呕吐控制率 :康泉为 85 3 % ,恩丹西酮为 79 4 %。两组结果的差异无显著性 (P均 >0 0 5)。认为恩丹西酮是一种强效止吐剂 ,且副反应轻微 ,每日 8mg剂量配合价廉的辅助药即可控制顺铂所致的恶心呕吐。 In order to further observe the control effect and dose of ondansetron on nausea and vomiting caused by cisplatin during chemotherapy, self-control methods were used to observe 34 cases of nausea and vomiting induced by cisplatin with Kangquan and ondansetron in different treatment cycles. As a result, the nausea control rate was 85 2% in Kangquan and 82 3% in ondansetron; the vomiting control rate was 85. 3% in Kangquan and 79.4% in ondansetron. There was no significant difference between the two groups (P > 0 05). It is considered that ondansetron is a potent antiemetic and the side effects are mild. Daily doses of 8mg combined with inexpensive adjuvant drugs can control cisplatin-induced nausea and vomiting.