神经肽Y(NPY)是一种新发现的广泛存在于中枢和周围神经系统内的多肽物质。它在许多方面调节或参与肾上腺素能神经的作用。它影响动物的LH 分泌和饮食行为,可能参与锥体外系运动功能的调节。它引起持久的血管平滑肌收缩,可能是造成冠状动脉痉挛的因素之一,并使心肌收缩力减弱。一些与儿茶酚胺有关的肿瘤如嗜铬细胞瘤组织以及这种病人的血液中都含有大量的NPY,它参与某些发病机制,测定它的含量还有诊断意义。 Neuropeptide Y (NPY) is a newly discovered class of polypeptide substances that are found extensively in the central and peripheral nervous system. It regulates or participates in the action of adrenergic nerves in many ways. It affects the animal’s LH secretion and eating behavior, may be involved in extrapyramidal motor function regulation. It causes long-lasting vascular smooth muscle contraction, may be one of the factors causing coronary spasm, and myocardial contractility weakened. Some catecholamine-related tumors such as pheochromocytoma and the patient’s blood contain large amounts of NPY, it is involved in some pathogenesis, determination of its content is also diagnostic.