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DIC 是ANLL 严重并发症之一,对ANLL 伴DIC患者纤溶与凝集系统的研究表明,这类病人可有多种凝血因子水平下降,但对于大组病例凝血因子状况进行系统研究尚未见报道,为此,作者对157例ANLL 病人凝血因子状况进行了调查,并着重探讨X 因子缺陷与DIC 的相关性。所有患者均为成年人,在治疗前进行凝血因子测定。如果(1)X 因子活性及抗原<50%及(2)其他肝合成的凝血因子(Ⅱ、Ⅴ、Ⅶ、Ⅸ)、血清白蛋白及拟胆碱酯酶在正常水平则为X 因子缺陷;X∶C 中度减少(50～70%)及肝合成蛋白在正常范围则为可疑X因子缺陷。ANLL 的诊断与分类采用FAB 联合小组标准。
DIC is one of the serious complications of ANLL. The study on the fibrinolytic and coagulative system of ANLL with DIC shows that there are many kinds of coagulation factors in these patients. However, there are no reports about the coagulation factors in a large group of cases. To this end, the author of 157 cases of ANLL patients coagulation factors were investigated, and focused on the X factor deficiency and DIC correlation. All patients were adults and clotting factors were measured prior to treatment. (1) Factor X activity and antigen <50%, and (2) coagulation factors (II, V, VII, IX) synthesized by other liver. Serum albumin and cholinesterase are normal X factor deficiencies; Moderate reduction in X: C (50-70%) and liver synthetic protein were suspect X-factor defects in the normal range. The diagnosis and classification of ANLL using FAB joint group standards.