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目的探讨慢性阻塞性肺疾病急性加重继发肺部真菌感染的临床治疗。方法对本院呼吸科2006～2009年收治的48例患者的临床表现、病因等临床资料进行回顾性分析。结果48例慢性阻塞性肺疾病急性加重继发肺部真菌感染的患者,痊愈22例,显效16例,进步8例,2例死亡,治疗有效率为79.2%(38/48)。结论确诊继发肺部真菌感染后,临床医生的首要任务是减少不合理用药,有针对性地改变抗生素应用策略,重视致病菌的检测,在正确选用抗真菌药的基础上加强支持治疗,尤其是免疫治疗,能缩短病程,改善患者的预后。
Objective To investigate the clinical treatment of pulmonary fungal infection after acute exacerbation of chronic obstructive pulmonary disease. Methods Retrospective analysis was performed on the clinical manifestations, etiology and other clinical data of 48 patients admitted to Department of Respiratory Medicine from 2006 to 2009 in our hospital. Results Forty-eight patients with COPD complicated by pulmonary fungal infection were cured, 22 cases were cured, 16 cases markedly improved, 8 cases improved, and 2 patients died. The effective rate was 79.2% (38/48). Conclusion The diagnosis of secondary pulmonary fungal infection, the clinician’s primary task is to reduce irrational medication, targeted changes in the application of antibiotics, attach importance to the detection of pathogens, the correct choice of antifungal agents based on the strengthening of supportive care, Especially immunotherapy, can shorten the course of disease, improve the prognosis of patients.