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目的:探讨前列腺内局限性弱回声灶与PSAD的关系,以提高对前列腺癌的早期检出率。方法:采用直肠超声法。结果:检出前列腺弱回声灶65例,范围0.5～2.0cm~2,84.61％位于移行区。病检证实前列腺癌(PCa)35例(53.84％),前列腺上皮内瘤(PIN)13例(20％),结节增生17例(26.15％)。以PSA10ng/ml和PSAD0.1为界值,对PCa和PIN的敏感性是52％和85％,特异性90％和56％,阳性预测值90％和71％。结论:前列腺弱回声灶和PSAD较单一指标能提高对前列腺癌的检出率。
Objective: To investigate the relationship between localized weak echogenic lesions in the prostate and PSAD in order to improve the early detection rate of prostate cancer. Methods: Rectal ultrasound was used. RESULTS: A total of 65 cases of prostate weak echogenic lesions were detected, ranging from 0.5 to 2.0 cm 2 and 84.61% in the transitional zone. The pathological examination confirmed prostate cancer (PCa) in 35 cases (53.84%), prostatic intraepithelial neoplasia (PIN) in 13 cases (20%), and nodular hyperplasia in 17 cases (26.15%). With a cutoff of PSA 10 ng/ml and PSAD 0.1, sensitivity to PCa and PIN was 52% and 85%, specificity was 90% and 56%, and positive predictive values were 90% and 71%. Conclusion: Prostate weak echogenic lesion and PSAD can improve the detection rate of prostate cancer compared with single index.