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目的:观察中西医结合方法治疗慢性盆腔炎的临床效果及其对细胞因子的影响。方法:将符合诊断标准的患者随机分为观察组(30例)和对照组(32例),分别采用化瘀止痛利湿中药内服、灌肠和单纯应用西药治疗,观察两组的近期临床疗效,细胞因子IL–2、IL–10等指标的变化情况。结果:观察组和对照组的总有效率分别为93.33%和71.89%,两组相比差异有统计学意义(P<0.05);两组治疗后升高患者的IL–2,IL–10,但观察组的上述作用显著优于对照组(P<0.05)。结论:化瘀止痛利湿中药内服、灌肠配合抗菌素治疗慢性盆腔炎的综合作用优于单纯使用抗菌素,其治疗机制可能与抗炎和免疫调节有关。
Objective: To observe the clinical efficacy of traditional Chinese and western medicine in the treatment of chronic pelvic inflammatory disease and its effect on cytokines. Methods: The patients who met the diagnostic criteria were randomly divided into observation group (n = 30) and control group (n = 32). The patients were treated with Huayu Zhitong Lishi Chinese herbs orally, enema and western medicine alone. The curative effect, Cytokines IL-2, IL-10 and other indicators of changes. Results: The total effective rate of the observation group and the control group were 93.33% and 71.89% respectively, there was significant difference between the two groups (P <0.05). The IL-2, IL-10, However, the above-mentioned effects of the observation group were significantly better than those of the control group (P <0.05). Conclusion: The comprehensive effects of Huayu Zhitonglixu Chinese herbal medicine and enema combined with antibiotics in treating chronic pelvic inflammatory disease are better than that of simply using antibiotics. The therapeutic mechanism may be related to anti-inflammation and immune regulation.