盐酸硫胺含量的测定方法,文献报道不下数十种,归纳起来可以分为三类:(一)仪器法,(二)容量法,(三)重量法。仪器法又分为分光光度法与萤光光度法。三类方法各有优缺点和适用范围。仪器法快速、选择性高,但需专用仪器和校正物质,误差也较大,常用于复方维生素B制剂的测定(分光法需先经过离子交换树脂的处理,将干扰物质分离)。容量法如非水碱量法、银量法等,有快速、简单、不需要贵重仪器等优点,缺点是选择性不高,仅适用于纯品的快速测定。重量法(硅钨 Determination of thiamine hydrochloride content, reported in the literature no fewer than dozens, summed up can be divided into three categories: (a) instrument method, (b) volumetric method, (c) gravimetric method. Instrumentation is divided into spectrophotometry and fluorescence spectrophotometry. Each of the three methods has its advantages and disadvantages and the scope of application. Instruments fast, high selectivity, but the need for special equipment and calibration substances, the error is also large, commonly used in the determination of compound vitamin B preparations (spectrophotometry need to go through ion exchange resin treatment, the interference material separation). Capacity method such as non-alkali method, the amount of silver method, a fast, simple, does not require expensive instruments, etc. The disadvantage is the selectivity is not high, only for the rapid determination of pure products. Gravimetric method (silicon tungsten