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冠状动脉痉挛在缺血性心脏病发病机理中的作用,探讨已有100余年。目前,通过冠状动脉造影,提示无论是在动物实验或变异型心绞痛患者,皆肯定了冠状动脉痉挛的作用。然而,迄今尚无确切资料能证明冠状动脉痉挛在慢性及急性心肌缺血中的主导作用,主要是由于冠状动脉造影本身就可以引起血管痉挛。本文报道对36例在发病后24小时内为解决外科治疗问题而进行了紧急冠状动脉造影术的急性心肌梗塞患者。心电图改变提示除1例外均为大面积心肌梗塞。冠状动脉造影显示25例病变区域的冠状动脉呈完全闭塞,另11例明显狭窄(2～3级)。4例患者
Coronary artery spasm in the pathogenesis of ischemic heart disease, to explore more than 100 years. At present, through coronary angiography, suggesting that both in animal experiments or patients with variant angina, are affirmed the role of coronary artery spasm. However, so far there is no definitive evidence that coronary artery spasm plays a dominant role in chronic and acute myocardial ischemia, mainly due to coronary angiography itself causing vasospasm. This article reports on 36 patients with acute myocardial infarction who underwent emergency coronary angiography to address the surgical treatment within 24 hours of onset. ECG changes prompted an exception except for a large area of myocardial infarction. Coronary angiography showed complete occlusion of the coronary arteries in 25 lesions and significant stenosis in the other 11 (grades 2 to 3). 4 patients