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为了解锌与锗是否具有协同或拮抗作用，对小鼠的血清、肝脏、肌肉进行了锌和锗含量、Ｔ淋巴细胞亚群百分比和超氧化物歧化酶（ＳＯＤ）活性、丙二醛（ＭＤＡ）含量测定。结果表明微量元素锌与锗在小鼠血清中有一定的竞争作用。锌含量高锗则低；锗含量高锌则低。血清锌、锗与肌肉、肝脏锌、锗及ＣＤ３、ＳＯＤ有一定的相关性。由于锌和锗含量的变化，小鼠免疫功能受到了影响，Ｔ淋巴细胞亚群发生改变。当两者联合应用时，血清锗高锌低，ＣＤ３、ＣＤ４降低、ＣＤ８不变，ＣＤ４／ＣＤ８比值下降，有一定的拮抗作用。在抗氧化能力方面，ＳＯＤ活性都有不同程度增高，而ＭＤＡ下降，两者没有拮抗作用
Zinc and germanium contents, T lymphocyte subsets and superoxide dismutase (SOD) activity, malondialdehyde (MDA) content in serum, liver and muscle of mice were determined to understand whether synergistic or antagonistic action of zinc and germanium. ) Content determination. The results show that trace elements zinc and germanium in mouse serum have a certain competitive effect. Germanium with high zinc content is low; germanium with high zinc content is low. Serum zinc, germanium and muscle, liver zinc, germanium and CD3, SOD have a certain correlation. Due to changes in the content of zinc and germanium, immune function was affected in mice, T lymphocyte subsets change. When the combination of the two, high germanium serum zinc low, CD3, CD4 decreased, CD8 unchanged, CD4 / CD8 ratio decreased, a certain antagonism. In antioxidant capacity, SOD activity increased to varying degrees, while MDA decreased, the two did not antagonize