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目的:银杏叶提取物近年来广泛用于心脑血管疾病的治疗,其治疗癫痫未见文献报道。本文对银杏叶提取物辅助抗癫痫疗效进行了临床研究。方法:采用开放性自身对照法,104例癫痫病人,在抗癫痫治疗至少3个月后,保持原抗癫痫药剂量不变,同时添加银杏叶提取物天保宁治疗。口服天保宁80mg,每日三次,共3个月。结果:添加天保宁治疗后每月平均发作次数由626±46次减少为257±52次(P<0.01)。每人平均发作16.1±9.2次/月减少为6.6±5.4次/月(P<0.01)。28例发作次数减少≥75％,33例发作次数减少≥50％,总有效率58.65％。无明显不良反应。结论:银杏叶提取物辅助治疗癫痫有效。
Objective: Ginkgo biloba extract is widely used in the treatment of cardiovascular and cerebrovascular diseases in recent years, and its treatment of epilepsy has not been reported in the literature. In this paper, Ginkgo biloba extract auxiliary anti-epileptic efficacy of a clinical study. Methods: The open self-control method, 104 cases of epilepsy patients, at least 3 months after the anti-epileptic treatment, maintaining the original anti-epileptic dose unchanged, while adding ginkgo biloba extract Tianbuling treatment. Oral Tianbao Ning 80mg, three times a day for a total of 3 months. Results: The average number of attacks per month after treatment was decreased from 626 ± 46 to 257 ± 52 (P <0.01). The average number of attacks per person was 16.1 ± 9.2 times / month decreased to 6.6 ± 5.4 times / month (P <0.01). The number of seizures decreased by 75% in 28 cases, the number of seizures decreased by 50% in 33 cases, and the total effective rate was 58.65%. No obvious adverse reactions. Conclusion: Ginkgo biloba extract is effective in treating epilepsy.