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对３９ 例ＮＩＤＤＭ 患者采用放射免疫法（ＲＩＡ）进行甘胆酸（ＣＧ）、透明质酸（ＨＡ）、分泌型免疫球蛋白Ａ（ｓＩｇＡ）、甲胎蛋白（ＡＦＰ）、铁蛋白（ＳＦ）、及癌胚抗原（ＣＥＡ）联合测定。以５１例健康人血清作对照。结果显示：ＮＩＤＤＭ患者血清ＳＦ、ＣＧ、ｓｌｇＡ与对照组比较有显著差异（Ｐ＜ ０．０１）；血清ＨＡ与对照组比较差异明显（Ｐ＜ ０．０５）；血清ＡＦＰ、ＣＥＡ则无差异（Ｐ＞ ０．０５）。检测结果说明对ＮＩＤＤＭ 患者血清ＳＦ、ＣＧ、ｓＩｇＡ、ＨＡ测定对诊断早期肝损伤具有可靠的临床价值。
39 cases of NIDDM patients were treated with radioimmunoassay (RIA) for the determination of glycine (HA), sIgA, AFP, SF, And carcinoembryonic antigen (CEA) joint determination. 51 healthy human serum as a control. The results showed that serum SF, CG, slgA in NIDDM patients were significantly different from those in control group (P <0.01); serum HA was significantly different from that in control group (P <0.05); serum AFP and CEA had no difference P> 0.05). The test results indicate that the determination of serum SF, CG, sIgA and HA in NIDDM patients has a reliable clinical value in the diagnosis of early liver injury.