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目的观察复方苦参注射液联合顺铂胸腔内注入治疗恶性胸腔积液的疗效。方法 70例恶性胸腔积液患者随机分为联合组(35例)、顺铂组(35例)。抽尽胸腔积液后,联合组向胸腔内注入复方苦参注射液加顺铂,顺铂组胸腔内只注入顺铂。观察两组患者治疗后的总有效率及胸水吸收情况。结果治疗后联合组总有效率82.8%,顺铂组68.6%,两组差异有统计学意义(P<0.05);治疗后联合组1个月内胸水吸收25例(71.4%),顺铂组11例(31.4%),两组差异有统计学意义(P<0.05)。结论复方苦参注射液联合顺铂胸腔内注入治疗恶性胸腔积液有确切疗效。
Objective To observe the curative effect of Compound Kushen Injection and Cisplatin in the treatment of malignant pleural effusion. Methods Seventy patients with malignant pleural effusion were randomly divided into combined group (35 cases) and cisplatin group (35 cases). After pleural effusion was drained, the combination group was injected with compound Kushen injection plus cisplatin into the thoracic cavity, and only cisplatin was injected into the cisplatin group. The total effective rate and pleural fluid absorption after treatment in both groups were observed. Results After treatment, the total effective rate was 82.8% in the combined group and 68.6% in the cisplatin group, with significant difference between the two groups (P <0.05); in the combined group, 25 cases (71.4% 11 cases (31.4%), the difference between the two groups was statistically significant (P <0.05). Conclusion Compound Kushen injection combined with cisplatin intrapleural injection of malignant pleural effusion have a definite effect.