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[目的]观察潘托拉唑加丽珠胃三联治疗难治性胃幽门螺杆菌(Hp)感染的疗效。[方法]80例经一线治疗失败的Hp感染患者,随机分为2组,治疗组予潘托拉唑加丽珠胃三联治疗,对照组予奥美拉唑、灭滴灵及克拉霉素治疗。[结果]治疗组Hp根除率为95.0%,对照组为51.4%,P<0.05。治疗组不良反应显著优于对照组。[结论]潘托拉唑加丽珠胃三联治疗难治性Hp感染疗效确切,不良反应少。
[Objective] To observe the curative effect of pantoprazole and clove stomach triple therapy on refractory gastric Hp infection. [Method] Eighty patients with Hp infection who failed the first-line treatment were randomly divided into two groups. The treatment group was treated with pantoprazole and carbaryl pearl triple therapy, and the control group with omeprazole, metronidazole and clarithromycin . [Results] The eradication rate of Hp in the treatment group was 95.0% and in the control group was 51.4%, P <0.05. Adverse reactions in the treatment group were significantly better than those in the control group. [Conclusion] The pantoprazole and carbaryl combined triple therapy in the treatment of refractory Hp infection has definite effect and few adverse reactions.