已知抗蠕虫消化和吸收宿主蛋白质关键酶的抗体 ,可通过影响肠道内蠕虫寄生的环境而成功介导抗蠕虫的免疫反应。作者将编码犬钩口线虫Ac TMP、Ac AP或Ac APR 1的重组载体转入原核或真核表达系统进行表达 ,将纯化的重组融合蛋白免疫接种犬。完成免疫接种后 ,用犬钩口线虫 3期感染 Antibodies known to be resistant to worms digesting and absorbing the key enzymes of host proteins can successfully mediate antihelmintic immune responses by affecting the environment in which intestinal worms parasitize. The authors transferred the recombinant vectors encoding Acinetobacter baumannii Ac TMP, Ac AP or Ac APR 1 into prokaryotic or eukaryotic expression systems for expression. The purified recombinant fusion proteins were immunized with dogs. After completing the immunization, the canine nematode stage 3 infection