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本文测定了50例肿瘤住院病例和50例非肿瘤住院病例的血清总胆固醇(T—C)、高密度脂蛋白胆固醇(HDL—C)及其比值HDL—C/T—C。并同时对病例和对照的吸烟、饮酒习惯和疾病等因素进行流行病学调查。病例与对照在年龄、性别、民族、居住地方面按1:1配对。配对分析结果表明:血清HDL—C、T—C与肿瘤呈显著负相关关系。分别调整性别、吸烟、饮酒因素后,只有HDL—C与肿瘤的反比关系在男性对子中、病例与对照同为吸烟者对子中、同为饮酒者对子中有高度显著性意义。在病例与对照同时为既吸烟又饮酒者对子中非常接近于显著性水平(P≈0.05)。本文虽无足够的证据认为血清T—C与肿瘤呈反比关系,但结果提示男性中肿瘤病人HDL—C值可能低于非肿瘤病人。
In this study, serum total cholesterol (T-C), high density lipoprotein cholesterol (HDL-C) and its ratio HDL-C / T-C were measured in 50 cancer inpatients and 50 non-tumor inpatients. At the same time, epidemiological investigation was conducted on cases and controls smoking, drinking habits and diseases. Cases and controls were paired 1: 1 by age, gender, ethnicity, and place of residence. Paired analysis showed that: serum HDL-C, T-C and tumor showed a significant negative correlation. Respectively adjust the gender, smoking, alcohol consumption factors, only the inverse relationship between HDL-C and cancer in male pairs, cases and controls with smoker pairs, with drinkers pairs of highly significant. In both cases and controls, both smoking and drinking pairs were very close to the significance level (P ≈ 0.05). Although there is not enough evidence to conclude that serum T-C is inversely proportional to the tumor, the results suggest that the HDL-C value of cancer patients may be lower than that of non-tumor patients in men.