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目的 总结子宫内膜间质肿瘤的病理学特点 ,讨论其诊断标准。方法 运用组织病理学、免疫组织化学方法并结合 12例患者随访材料。结果 肿瘤的大体形态有 3种 :宫腔内呈息肉状、肌壁间结节状及脉管中蚯蚓状。肿瘤的镜下特点 :子宫内膜间质结节 ( ESN)和低度恶性子宫内膜间质肉瘤 ( L GESS)组织学表现相似。二者鉴别要点在于 L GESS具有浸润性生长和脉管内生长的特性。L GESS和高度恶性子宫内膜间质肉瘤 ( HGESS)的鉴别要点是后者具明显异型性。结论 肿瘤有否浸润及细胞成分是否单一是确定本瘤性质及排除其他恶性肿瘤的条件
Objective To summarize the pathological features of endometrial stromal tumors and discuss the diagnostic criteria. Methods Histopathology, immunohistochemical methods and 12 cases were followed up. Results The general morphology of the tumor there are three kinds: intrauterine polypoid, intramural nodules and vessels in the earthworm-shaped. Microscopic features of tumors: Histological findings of endometrial interstitial nodules (ESN) and low-grade endometrial stromal sarcoma (L GESS) are similar. The main points of identification between the two are that L GESS has the characteristics of infiltrative growth and intravascular growth. L GESS and highly malignant endometrial stromal sarcoma (HGESS) The main points of identification is the latter with significant atypia. Conclusion Whether the tumor infiltrates and whether the cell components are single is to determine the nature of the tumor and rule out other malignant tumors