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目的:观察血液透析联合血液灌流对慢性肾功能衰竭患者血脂的影响。方法:选取在西安交通大学医学院第二附属医院长期进行血液净化治疗的慢性肾功能衰竭患者39例,分别给予常规透析、血液透析联合血液灌流治疗,观察治疗前后血脂成分包括甘油三酯(TG)、胆固醇(TC)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、脂蛋白A[Lp(a)]等的变化。结果:常规透析治疗前后血脂成分无明显变化。血液透析联合血液灌流患者治疗后TG、Lp(a)较治疗前显著下降,TC、HDL以及LDL在治疗前后差异无显著性。结论:血液透析联合血液灌流治疗能够改善慢性肾功能衰竭患者的部分脂质代谢异常。
Objective: To observe the effect of hemodialysis combined with hemoperfusion on blood lipids in patients with chronic renal failure. Methods: Thirty-nine patients with chronic renal failure treated by long-term blood purification treatment at the Second Affiliated Hospital of Xi’an Jiaotong University School of Medicine were enrolled. They were given routine hemodialysis and hemodialysis combined with hemoperfusion. The levels of triglyceride (TG) ), Cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), lipoprotein A [Lp (a)] and so on. Results: There was no significant change in blood lipid composition before and after routine dialysis. After treatment with hemodialysis combined with hemoperfusion, the levels of TG and Lp (a) decreased significantly compared with those before treatment. The levels of TC, HDL and LDL had no significant difference before and after treatment. Conclusion: Hemodialysis and hemoperfusion can improve some lipid metabolism abnormalities in patients with chronic renal failure.