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目的 探讨80岁及以上超高龄患者行腹腔镜胆囊切除术(laparoscopic cholecystectomy,LC)的安全性和可行性.方法 回顾分析2010年12月-2015年12月,159例行腹腔镜胆囊切除术的80岁及以上高龄患者的围术期资料,按年龄划分高龄A组(80～84岁),超高龄B组(85岁以上)对比二组手术情况、术后并发症、术后住院时间、死亡率等.结果 二组在手术时间、术中出血量、中转开腹率、术后住院时间、术后总体并发症、术后死亡率中差异均无统计学意义(P＞0.05).结论 全面术前评估患者对手术的耐受情况,术前多学科协作积极处理并存疾病,注意全程贯彻加速康复外科及损伤控制理念,监测生命体征变化,对超高龄患者行LC安全可靠.“,”Objective To evaluate the safety and feasibility of laparoscopic cholecystectomy (LC) in patients over 80 years old.Methods Between Dec 2012 and Dec 2015,159 patients of over 80 years old underwent LC surgery,all of the patients during perioperative period were analyzed,included that average duration of surgery,mean blood loss,mortality and postoperative hospital day.Results Two groups in operative time,intraoperative blood loss,open rate,postoperative hospital stay,postoperative complications,postoperative mortality in the general differences had no statistical significance(P＞0.05).Conclusions Properperi-operative management effective control of co-morbidities,and careful surgical performance are essential for a safe LC in patients the age of 80 or more.