论文部分内容阅读
目的对散发性脑炎患者的临床特征、早期诊断以及疾病的转归进行探讨。方法选取2007年3月至2012年3月5年来我院进行治疗的符合“散发性脑炎”临床诊断标准的52例患者的临床资料进行回顾性分析。结果 52例患者均表现有不同程度的头痛、恶心、呕吐的共有27例(51.92%),以癫痫为首发症状的有13例(25.00%),表现为昏迷的有3例(5.77%),首发症状为精神症状的有6例(11.54%),偏瘫2例(3.85%);经脑脊液检查出现异常的有28例(53.85%);影像学检查中头颅CT检查异常的有2(3.85%)例,脑脊液穿刺检查发现糖、氯化物以及脑脊液细胞数等在正常范围的分别为74.51%、52.95%和69.47%;蛋白正常的有51.49%;有32.64%的患者出现外周血中白细胞升高,主要以中性粒细胞为主,淋巴细胞升高的仅有11.15%。患者在出院后进行为期1年的随访,在52例患者当中,治愈率为64.53%,好转率为30.14%,病死率为0.89%,失随访率为4.44%。结论散发性脑炎的临床指征多样,应结合相关检查进行综合分析才能进行诊断,仅凭一种症状或体征不能确诊。散发性脑炎患者通常预后良好。
Objective To investigate the clinical features, early diagnosis and prognosis of patients with sporadic encephalitis. Methods The clinical data of 52 patients who met the criteria of “sporadic encephalitis” in our hospital from March 2007 to March 2012 were retrospectively analyzed. Results A total of 52 patients showed headache, nausea and vomiting in 27 cases (51.92%), epilepsy in 13 cases (25.00%), coma in 3 cases (5.77%), There were 6 cases (11.54%) with hemiplegia and 28 cases (53.85%) with abnormal cerebrospinal fluid in the first symptom of psychosis. There were 2 (3.85% ) Cases, cerebrospinal fluid puncture examination found that the number of cells in the normal range of sugar, chloride and cerebrospinal fluid were 74.51%, 52.95% and 69.47%; 51.49% of normal protein; 32.64% of patients with peripheral leukocytosis , Mainly in neutrophils, only 11.15% of lymphocytes increased. Among the 52 patients, the cure rate was 64.53%, the improvement rate was 30.14%, the case fatality rate was 0.89%, and the follow-up rate was 4.44%. Conclusions The clinical indications of sporadic encephalitis are diverse and should be combined with related tests to make a comprehensive analysis to diagnose them. Only one kind of symptoms or signs can not be diagnosed. Patients with sporadic encephalitis usually have a good prognosis.