胰岛素样生长因子（ＩＧＦｓ）及其受体、结合蛋白、结合蛋白酶构成ＩＧＦ轴，在机体营养代谢和免疫功能的成熟中起重要调节作用。ＩＧＦｓ能促进蛋白质的合成，促进葡萄糖氧化与脂肪分解，同时可保护肠道粘膜屏障，促进免疫细胞分化与成熟。提示重组人胰岛素样生长因子可望成为肠道外营养的重要组成部分。 Insulin-like growth factors (IGFs) and their receptors, binding proteins and binding proteases constitute the IGF axis and play an important regulatory role in the body’s nutrition metabolism and immune function maturation. IGFs can promote protein synthesis, promote glucose oxidation and lipolysis, while protecting the intestinal mucosal barrier, and promote immune cell differentiation and maturation. Tip recombinant human insulin-like growth factor is expected to become an important part of parenteral nutrition.