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为探讨“航天贫血症”的起因，观察了头低位－３０°尾吊组大鼠在实验第７、１５、３０天时的红细胞变形性、膜流动性及细胞形态。结果表明：（１）与对照组相比，尾吊鼠红细胞变形性（ＤＩｍａｘ和ＩＤＩ）在实验第７天已明显降低（Ｐ＜０．０５），第１５天进一步下降（Ｐ＜０．０１），第３０天有所恢复，但仍显著低于对照组（Ｐ＜０．０５）；（２）两组红细胞膜流动性在实验第７天无明显差别，但在第１５天和３０天时，尾吊组的红细胞膜流动性明显降低（Ｐ＜０．０１）；（３）实验期间尾吊鼠血中异形红细胞比例较对照组增加。提示，模拟失重改变了红细胞的流变特性及形态，这可能是导致“航天贫血症”的重要起因之一。
To explore the causes of “space anemia”, the erythrocyte deformability, membrane fluidity and cell morphology were observed at the 7th, 15th and the 30th day in the head-tail-30 ° tail suspension group. The results showed that: (1) Compared with the control group, the erythrocyte deformability (DImax and IDI) in the tail hamster was significantly decreased on the 7th day (P <0.05) and further decreased on the 15th day (P <0.01) (P <0.05). (2) The fluidity of erythrocyte membrane in the two groups had no significant difference on the 7th day, but on the 15th and 30th day , And the fluidity of erythrocyte membrane in the tail suspension group was significantly decreased (P <0.01). (3) The proportion of tail blood-shaped red blood cells increased in the tail hamster than that in the control group. It is suggested that simulated weightlessness changes the rheological properties and morphology of erythrocytes, which may be one of the important causes of “space anemia”.