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运用免疫组织化学技术——S-P 法,检测了78例肺癌组织中的 P~(53)抑癌基因产物——P~(53)蛋白的表达。结果发现肺癌组织的 P~(53)蛋白表达率为53.8%(42/78)。从而进一步证实了 P~(53)抑癌基因突变与肺癌的关系。
Using immunohistochemical technique, S-P method, the expression of P53 tumor suppressor gene P53 protein was detected in 78 lung cancer tissues. As a result, the expression rate of P53 protein in lung cancer tissues was 53.8% (42/78). This further confirmed the relationship between P53 tumor suppressor gene mutations and lung cancer.