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室内抗药性筛选表明 ,褐飞虱对甲胺磷的抗性呈“快 -慢 -快”的发展趋势 :第 1到第 4代抗性上升缓慢 ;第 5代到第 15代迅速上升 ,其中又呈现 2个发展阶段 ,以第 9代为拐点 ;第 15代后抗性上升变慢。羧酸酯酶在抗药性上升中可能起到十分重要的作用 ,与 L D50 变化存在很高的相关性 ,达到极显著水平 ,相关系数为 0 .990 6。乙酰胆碱酯酶不敏感性在抗性发展后期变化很大 ,第 8代到第16代间 ,与 L D50 变化存在极显著相关性 ,相关系数为 0 .970 1。由此可见 ,羧酸酯酶可能在褐飞虱对甲胺磷抗性的持续发展中起十分重要的作用 ,而乙酰胆碱酯酶不敏感性在抗性发展的后期阶段可能起到很重要作用
The results of indoor resistance screening showed that the resistance of BPH to methamidophos showed a trend of “fast-slow-fast”: the resistance of the first to fourth generations increased slowly; the fifth to the fifteenth generations rose rapidly, 2 stages of development, with the 9th generation as the inflection point; After the 15th generation, the resistance increased slowly. Carboxylesterase may play a very important role in the rise of drug resistance and has a very high correlation with the change of L D50 at a very significant level with a correlation coefficient of 0.9906. The insensitivity of acetylcholinesterase varied greatly in the late stage of resistance development. Between the 8th generation and the 16th generation, there was a very significant correlation with the change of L D50 with a correlation coefficient of 0.9701. Thus, carboxylesterase may play a very important role in the sustained development of methamidophos resistance in N. lugens, whereas the insensitivity of acetylcholinesterase may play an important role in the later stage of resistance development