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目的观察乡镇卫生院剖宫产围手术期规范应用抗生素的效果。方法将符合入选标准的剖宫产孕妇194例分为观察组(98例)和对照组(96例)。观察组于术中断脐后立即予头孢呋辛钠静脉给药,术后每8 h给药1次,共3次。对照组术后回病房予头孢呋辛钠静脉给药,术后每8 h给药1次,共7 d。出院后随访3周,比较2组术后感染率、住院天数、住院费用及抗生素使用费用等指标。结果观察组的术后感染率、平均住院天数、住院费用及抗生素使用费用等指标均优于对照组(P<0.05或P<0.01)。结论规范短疗程头孢呋辛钠预防剖宫产术后感染效果优于传统长疗程头孢呋辛钠,并明显降低平均住院天数、住院费用,可作为乡镇卫生院剖宫产手术预防感染首选方案。
Objective To observe the effect of standard antibiotics on cesarean section perioperative period in township hospitals. Methods One hundred and ninety-four pregnant women of cesarean section who met the inclusion criteria were divided into observation group (n = 98) and control group (n = 96). The observation group received intravenous cefuroxime sodium immediately after the umbilical cord was cut off, and administered once every 8 hours for 3 times. Control group postoperative ward to cefuroxime sodium intravenous administration, once every 8 h after surgery, a total of 7 d. Followed up for 3 weeks after discharge, compared the incidence of postoperative infection, hospitalization days, hospitalization costs and antibiotic use costs. Results The postoperative infection rate, average hospitalization days, hospitalization expenses and antibiotic use cost in the observation group were all better than those in the control group (P <0.05 or P <0.01). Conclusion Standard short-term treatment of cefuroxime sodium after cesarean section to prevent infection is better than the traditional long-term course of cefuroxime sodium, and significantly reduce the average length of stay in hospital, hospital costs, cesarean section township hospitals can be used as the preferred program of prevention of infection.