纳米颗粒是指空气动力学直径1～100 nm的颗粒。一般认为纳米颗粒的潜在健康危害要高于微米级颗粒,因为质量相同的纳米颗粒与微米颗粒相比,计数浓度高,且具有更大的表面积和表面活性〔1-2〕。纳米颗粒主要经呼吸道吸入机体,由于其粒径细小,纳米颗粒能够穿过气血屏障直接进 Nanoparticles are particles with an aerodynamic diameter of 1 to 100 nm. It is generally considered that the potential health hazard of nanoparticles is higher than that of micron-sized particles, since the nanoparticles of the same mass have higher counted concentration and larger surface area and surface activity than microparticles [1-2]. Nanoparticles inhaled mainly through the respiratory tract, due to their small size, nanoparticles can be directly through the blood-barrier