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目的 :利用部分“边缘肾” ,或因血型特殊局部地区无适合受体的供肾进行双肾移植 ,探讨双肾移植的临床疗效。 方法 :自 2 0 0 1年 3月至 2 0 0 2年 1 0月 ,我们共利用该类“边缘肾”与“无人要的肾脏”为 8例患者进行了双肾移植。采用右下腹“L”型切口 ,来自 8个供体的 1 6个肾脏被分别移植于 8例受者的右侧髂窝内。免疫抑制方案为皮质激素 +霉酚酸酯 +环孢素A ,剂量同单肾移植。 结果 :在 1～ 1 2个月的随访期内发生急性排斥(AR) 2例共 2次 (2 5 % ) ,1只肾由于肾动脉栓塞失功。 5例随访 1 2个月肾功能均正常。 结论 :双边缘肾移植有助于充分利用日趋紧张的肾源 ,提供给患者更多的有效肾单位。肾移植的免疫抑制方案 ,AR发生率 ,与单肾移植效果相同
OBJECTIVE: To investigate the clinical efficacy of double renal transplantation by using partial “marginal kidney” or bilateral renal transplantation for donors with no specific receptor in the blood type. METHODS: From March 2001 to October 2002, we performed a total of 8 renal transplantations in 8 patients with this type of “marginal kidney” and “uninvited kidney.” Using a right lower quadrant “L” incision, 16 kidneys from 8 donors were transplanted into the right iliac fossa of 8 recipients, respectively. Immunosuppressive programs for corticosteroids + mycophenolate mofetil + cyclosporine A, the same dose with the single kidney transplant. Results: Acute rejection (AR) occurred in 2 cases (25%) during the follow-up period of 1 to 12 months. One renal failure occurred due to renal artery embolization. Five cases were followed up for 12 months, the renal function were normal. CONCLUSIONS: Dual-limbic kidney transplantation helps to take full advantage of increasingly tense kidney sources to provide patients with more effective nephrons. The immunosuppressive regimen of kidney transplantation, the incidence of AR, is the same as the single kidney transplant